Functions of Chitosan-Ferulic Acid Salt for Prevention of Hypertension

被引：11

作者：

Murata, Yoshifumi ^{[1
]}

Nagaki, Kumiko ^{[1
]}

Kofuji, Kyoko ^{[1
]}

Kishi, Toshihiro ^{[2
]}

机构：

[1] Hokuriku Univ, Fac Pharmaceut Sci, Kanazawa, Ishikawa 9201181, Japan

[2] Nippon Suisan Ltd, Chiyoda Ku, Tokyo 1008686, Japan

来源：

FOOD SCIENCE AND TECHNOLOGY RESEARCH | 2010年 / 16卷 / 05期

关键词：

ferulic acid; chitosan; anti-hypertensive effect; bile acid adsorption; alginate gel bead; ANTIOXIDANT ACTIVITY; DIABETIC-RATS;

D O I：

10.3136/fstr.16.437

中图分类号：

TS2 [食品工业];

学科分类号：

100403 [营养与食品卫生学];

摘要：

A chitosan (CS)-ferulic acid (FA) salt was prepared. FA release from CS-FA and bile acid (BA) adsorption by CS-FA were investigated in vitro. CS-FA released FA into artificial gastric juice or a medium containing BA. Two functions were recognized on alginate or pectin gel beads containing CS-FA: FA release and BA adsorption. Anti-hypertensive effects of CS, FA or CS-FA on hypertensive rats were tested. In rats given a diet containing CS-FA or FA, elevation of systolic blood pressure was suppressed compared to the control diet group, but no difference in food intake or body weight was observed between groups.

引用

页码：437 / 442

页数：6

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