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Chronic eosinophilic leukemia and hypereosinophilic syndromes - Proposal for classification, literature review, and report of a case with a unique chromosomal abnormality
被引:43
作者:
Oliver, JW
Deol, I
Morgan, DL
Tonk, VS
机构:
[1] Texas Tech Univ, Hlth Sci Ctr, Dept Pathol, Lubbock, TX 79430 USA
[2] Texas Tech Univ, Hlth Sci Ctr, Dept Pathol, El Paso, TX USA
[3] Texas Tech Univ, Hlth Sci Ctr, Dept Pediat, Lubbock, TX 79430 USA
关键词:
D O I:
10.1016/S0165-4608(98)00099-5
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
The idiopathic hypereosinophilic syndromes (HES) are rare hematologic disorders characterized by persistent eosinophilia with organ involvement that encompass a wide spectrum of clinical and hematological disease states. We propose a classification scheme to further delineate these patients, and present a case of a 45-year-old male with persistent eosinophilia, ser ere tissue and hematologic involvement, and trisomy 15. Although multiple cytogenetic abnormalities have been associated with hypereosinophilic syndromes, this is the first reported case where trisomy 15 is the sole chromosomal abnormality. (C) Elsevier Science Inc., 1998.
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页码:111 / 117
页数:7
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