Nanomaterial-based electrochemical biosensors for medical applications

被引：167

作者：

Kerman, Kagan ^{[2
]}

Saito, Masato ^{[1
]}

Yamamura, Shohei ^{[3
]}

Takamura, Yuzuru ^{[3
]}

Tamiya, Eiichi ^{[1
]}

机构：

[1] Japan Adv Inst Sci & Technol, Sch Mat Sci, Nomi City, Ishikawa 9231292, Japan

[2] Univ Western Ontario, Dept Chem, London, ON N6A 5B7, Canada

[3] Osaka Univ, Grad Sch Engn, Dept Appl Phys, Osaka 5670047, Japan

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2008年 / 27卷 / 07期

关键词：

biosensor; carbon nanotube; colloidal gold nanoparticle; electrochemical; field-effect transistor; label-free; medical; metal nanoparticle; nanomaterial; tyrosine oxidation;

D O I：

10.1016/j.trac.2008.05.004

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

With recent advances in nanotechnology, great progress has been made in biosensors based on nanomaterials, but there are still numerous challenges to overcome. We describe nanomaterial-based biosensors for researchers new to the field, paying particular attention to metal nanoparticles and carbon nanotube (CNT)-based label-free approaches. Label-free monitoring of biorecognition events provides a promising platform, which is simple, cost-effective, and requires no external modification to biomolecules. Using examples from recent reports, we illustrate the diversity of biological recognition events and the range of experimental techniques employed for metal-nanoparticle-based and label-free characterization. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：585 / 592

页数：8

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