Sulpholane - A new solvent for the Baylis-Hillman reaction

被引:48
作者
Krishna, PR [1 ]
Manjuvani, A [1 ]
Kannan, V [1 ]
Sharma, GVM [1 ]
机构
[1] Indian Inst Chem Technol, Discovery Lab, Div Organ Chem 3, Hyderabad 500007, Andhra Pradesh, India
关键词
Baylis-Hillman reactions; sulpholane; aprotic polar solvent; DABCO; activated olefins;
D O I
10.1016/j.tetlet.2003.11.137
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Sulpholane, a commercially available solvent, is used for the first time as a new solvent for the Baylis-Hillman reaction tinder ambient conditions; a wide variety of olefins as well as aldehydes participate very efficiently resulting in good to excellent yields of products. Acrylamide also underwent the Baylis-Hillman reaction with 4-nitrobenzaldehyde under these reaction conditions. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1183 / 1185
页数:3
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