Reusable, label-free electrochemical aptasensor for sensitive detection of small molecules

被引:70
作者
Li, Bingling
Du, Yan
Wei, Hui
Dong, Shaojun [1 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
关键词
D O I
10.1039/b707057h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a sensitive electrochemical aptasensor for adenosine based on electrochemical impedance spectroscopy measurement, which gives not only a label-free but also a reusable platform to make the detection of small molecules simple and convenient.
引用
收藏
页码:3780 / 3782
页数:3
相关论文
共 35 条
[1]  
Baker BR, 2006, J AM CHEM SOC, V128, P3138, DOI 10.1021/ja056957p
[2]  
BOON EM, 2002, THESIS CLAIFORNIA I
[3]   Label-free protein recognition using an aptamer-based impedance measurement assay [J].
Cai, H ;
Lee, TMH ;
Hsing, IM .
SENSORS AND ACTUATORS B-CHEMICAL, 2006, 114 (01) :433-437
[4]   INVITRO SELECTION OF RNA MOLECULES THAT BIND SPECIFIC LIGANDS [J].
ELLINGTON, AD ;
SZOSTAK, JW .
NATURE, 1990, 346 (6287) :818-822
[5]   Study of binding stoichiometries of the human immunodeficiency virus type 1 reverse transcriptase by capillary electrophoresis and laser-induced fluorescence polarization using aptamers as probes [J].
Fu, H ;
Guthrie, JW ;
Le, XC .
ELECTROPHORESIS, 2006, 27 (02) :433-441
[6]   Quantum-dot/aptamer-based ultrasensitive multi-analyte electrochemical biosensor [J].
Hansen, JA ;
Wang, J ;
Kawde, AN ;
Xiang, Y ;
Gothelf, KV ;
Collins, G .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (07) :2228-2229
[7]   A DNA APTAMER THAT BINDS ADENOSINE AND ATP [J].
HUIZENGA, DE ;
SZOSTAK, JW .
BIOCHEMISTRY, 1995, 34 (02) :656-665
[8]   Signaling aptamer/protein binding by a molecular light switch complex [J].
Jiang, YX ;
Fang, XH ;
Bai, CL .
ANALYTICAL CHEMISTRY, 2004, 76 (17) :5230-5235
[9]  
Li JWJ, 2002, NANO LETT, V2, P315, DOI 10.1021/n1015713+
[10]   Adaptive recognition of small molecules by nucleic acid aptamers through a label-free approach [J].
Li, Tao ;
Li, Bingling ;
Dong, Shaojun .
CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (23) :6718-6723