学术探索
学术期刊
新闻热点
数据分析
智能评审

Systematic functional analysis of the yeast genome

被引：817
作者：
Oliver, SG
Winson, MK
Kell, DB
Baganz, F
机构：
[1] Univ Manchester, Dept Biomol Sci, Manchester M60 1QD, Lancs, England
[2] Univ Wales, Inst Biol Sci, Aberystwyth SY23 3DD, Dyfed, Wales
来源：
TRENDS IN BIOTECHNOLOGY | 1998年 / 16卷 / 09期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/S0167-7799(98)01214-1
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The genome sequence of the yeast Saccharomyces cerevisiae has provided the first complete inventory of the working parts of a eukaryotic cell. The challenge is now to discover what each of the gene products does and how they interact in a living yeast cell. Systematic and comprehensive approaches to the elucidation of yeast gene function are discussed and the prospects for the functional genomics of eukaryotic organisms evaluated.
引用
收藏
页码：373 / 378
页数：6
相关论文
共 51 条
  • [21] LINEAR STEADY-STATE TREATMENT OF ENZYMATIC CHAINS - GENERAL PROPERTIES, CONTROL AND EFFECTOR STRENGTH
    HEINRICH, R
    RAPOPORT, TA
    [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1974, 42 (01): : 89 - 95
  • [22] Functional genomics: It's all how you read it
    Hieter, P
    Boguski, M
    [J]. SCIENCE, 1997, 278 (5338) : 601 - 602
  • [23] Oligomer-chip technology
    Hoheisel, JD
    [J]. TRENDS IN BIOTECHNOLOGY, 1997, 15 (11) : 465 - 469
  • [24] Kacser H, 1973, Symp Soc Exp Biol, V27, P65
  • [25] METABOLIC CONTROL-THEORY - ITS ROLE IN MICROBIOLOGY AND BIOTECHNOLOGY
    KELL, DB
    WESTERHOFF, HV
    [J]. FEMS MICROBIOLOGY LETTERS, 1986, 39 (04) : 305 - 320
  • [26] KELL DB, 1989, SYMP SOC GEN MICROBI, V44, P61
  • [27] Expression monitoring by hybridization to high-density oligonucleotide arrays
    Lockhart, DJ
    Dong, HL
    Byrne, MC
    Follettie, MT
    Gallo, MV
    Chee, MS
    Mittmann, M
    Wang, CW
    Kobayashi, M
    Horton, H
    Brown, EL
    [J]. NATURE BIOTECHNOLOGY, 1996, 14 (13) : 1675 - 1680
  • [28] Why and when channelling can decrease pool size at constant net flux in a simple dynamic channel
    Mendes, P
    Kell, DB
    Westerhoff, HV
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1996, 1289 (02): : 175 - 186
  • [29] Naumann Dieter, 1996, P279
  • [30] A STRATEGY FOR INCREASING AN INVIVO FLUX BY GENETIC MANIPULATIONS - THE TRYPTOPHAN SYSTEM OF YEAST
    NIEDERBERGER, P
    PRASAD, R
    MIOZZARI, G
    KACSER, H
    [J]. BIOCHEMICAL JOURNAL, 1992, 287 : 473 - 479
123456