Primary intestinal epithelial cells can be infected with laboratory-adapted strain HIV type 1 NDK but not with clinical primary isolates

被引：11

作者：

Chenine, AL

Matouskova, E

Sanchez, G

Reischig, J

Pavlikova, L

LeContel, C

Chermann, JC

Hirsch, I

机构：

[1] INSERM U372, Unite Pathogenie Infect Lentivirus, F-13273 Marseille 09, France

[2] INSERM U372, Unite Pathogenie Infect Lentivirus, F-13273 Marseille, France

[3] Acad Sci Czech Republ, Inst Mol Genet, Prague, Czech Republic

[4] Charles Univ, Fac Med, Dept Biol, Plzen, Czech Republic

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 1998年 / 14卷 / 14期

关键词：

D O I：

10.1089/aid.1998.14.1235

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Infectivities of HIV-1 primary isolates and laboratory-adapted strains were compared in primary fetal enterocytes and the colonic epithelial cell line HT29. Infection by two laboratory strains, HIV-1 NDK and HIV-1 NDKA4, which were adapted on CEM and HT29 cells, respectively, produced significant amounts of virus in both target cell systems. Intestinal cells were resistant to infection with HIV-1 primary isolates regardless of their genetic subtype or SI/NSI phenotype, Biological properties of analyzed viruses rather than differences in cultivation system seem to be responsible for differences between these in vitro and ex vivo results.

引用

页码：1235 / 1238

页数：4

共 19 条

[11] INFECTION OF HUMAN GASTROINTESTINAL CELLS BY HIV-1 [J].

MOYER, MP ;

HUOT, RI ;

RAMIREZ, A ;

JOE, S ;

MELTZER, MS ;

GENDELMAN, HE .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1990, 6 (12) :1409-1415

[12]

NELSON JA, 1988, LANCET, V1, P259

[13] HIV-1 INFECTION AND EXPRESSION IN HUMAN COLONIC CELLS - INFECTION AND EXPRESSION IN CD4+ AND CD4- CELL-LINES [J].

OMARY, MB ;

BRENNER, DA ;

DEGRANDPRE, LY ;

ROEBUCK, KA ;

RICHMAN, DD ;

KAGNOFF, MF .

AIDS, 1991, 5 (03) :275-281

[14] HIV TYPE-1 VARIATION IN WORLD-HEALTH-ORGANIZATION-SPONSORED VACCINE EVALUATION SITES - GENETIC SCREENING, SEQUENCE-ANALYSIS, AND PRELIMINARY BIOLOGICAL CHARACTERIZATION OF SELECTED VIRAL STRAINS [J].

OSMANOV, S ;

BELSEY, EM ;

HEYWARD, W ;

ESPARZA, J ;

GALVAOCASTRO, B ;

VANDEPERRE, P ;

KARITA, E ;

WASI, C ;

SEMPALA, S ;

TUGUME, B ;

BIRYAHWAHO, B ;

RUBSAMENWAIGMANN, H ;

VONBRIESEN, H ;

ESSER, R ;

GREZ, M ;

HOLMES, H ;

NEWBERRY, A ;

RANJBAR, S ;

TOMLINSON, P ;

BRADAC, J ;

MCCUTCHAN, F ;

LOUWAGIE, J ;

HEGERICH, P ;

LOPEZGALINDEZ, C ;

OLIVARES, I ;

DOPAZO, J ;

MULLINS, JI ;

DELWART, EL ;

BACHMANN, HM ;

GOUDSMIT, J ;

DEWOLF, F ;

HAHN, BH ;

GAO, F ;

YUE, L ;

SARAGOSTI, S ;

SCHOCHETMAN, G ;

KALISH, M ;

LUO, CC ;

GEORGE, R ;

PAU, CP ;

WEBER, J ;

CHEINGSONGPOPOV, R ;

KALEEBU, P ;

NARA, P ;

FENYO, EM ;

ALBERT, J ;

MYERS, G ;

KORBER, B .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1994, 10 (11) :1327-1343

[15] PRODUCTIVE INFECTION OF CD4+ CELLS BY SELECTED HIV STRAINS IS NOT INHIBITED BY ANTI-CD4 MONOCLONAL-ANTIBODIES [J].

REY, F ;

DONKER, G ;

HIRSCH, I ;

CHERMANN, JC .

VIROLOGY, 1991, 181 (01) :165-171

[16] SERIAL CULTIVATION OF STRAINS OF HUMAN EPIDERMAL KERATINOCYTES - FORMATION OF KERATINIZING COLONIES FROM SINGLE CELLS [J].

RHEINWALD, JG ;

GREEN, H .

CELL, 1975, 6 (03) :331-344

[17] NUCLEOTIDE-SEQUENCE OF HIV1-NDK - A HIGHLY CYTOPATHIC STRAIN OF THE HUMAN IMMUNODEFICIENCY VIRUS [J].

SPIRE, B ;

SIRE, J ;

ZACHAR, V ;

REY, F ;

BARRESINOUSSI, F ;

GALIBERT, F ;

HAMPE, A ;

CHERMANN, JC .

GENE, 1989, 81 (02) :275-284

[18] ESTABLISHMENT OF CONDITIONALLY IMMORTALIZED EPITHELIAL-CELL LINES FROM BOTH COLON AND SMALL-INTESTINE OF ADULT H-2KB-TSA58 TRANSGENIC MICE [J].

WHITEHEAD, RH ;

VANEEDEN, PE ;

NOBLE, MD ;

ATALIOTIS, P ;

JAT, PS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (02) :587-591

[19] GALACTOSYL CERAMIDE (OR A CLOSELY RELATED MOLECULE) IS THE RECEPTOR FOR HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ON HUMAN COLON EPITHELIAL HT29 CELLS [J].

YAHI, N ;

BAGHDIGUIAN, S ;

MOREAU, H ;

FANTINI, J .

JOURNAL OF VIROLOGY, 1992, 66 (08) :4848-4854

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