The evolving role of platelets in inflammation

被引:222
作者
Weyrich, AS
Lindemann, S
Zimmerman, GA
机构
[1] Univ Utah, Dept Internal Med, Salt Lake City, UT 84112 USA
[2] Univ Utah, Eccles Inst Human Genet, Salt Lake City, UT 84112 USA
[3] Johannes Gutenberg Univ Mainz, Dept Med, Mainz, Germany
关键词
inflammation; platelets; translation;
D O I
10.1046/j.1538-7836.2003.00304.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Platelets are small in size and simple in structure. Nevertheless, these anucleate cytoplasts utilize complex molecular systems to regulate a variety of biological functions. Here we review evolutionary paths, traditional roles, and previously unrecognized biological capacities of platelets that interface thrombosis with inflammation and potentially identify new roles in inflammatory diseases.
引用
收藏
页码:1897 / 1905
页数:9
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