A seminal finding for understanding HIV transmission

被引:22
作者
Roan, Nadia R. [1 ]
Greene, Warner C. [1 ]
机构
[1] Univ Calif San Francisco, Gladstone Inst Virol & Immunol, San Francisco, CA 94158 USA
关键词
D O I
10.1016/j.cell.2007.11.030
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Although the worldwide incidence of HIV infection is high, the retrovirus displays a surprisingly low infectivity in vitro. As a potential explanation for this discrepancy, Munch et al. (2007) now identify and characterize a factor found in human semen that under certain conditions can enhance HIV infectivity by more than 100,000-fold.
引用
收藏
页码:1044 / 1046
页数:3
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