Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives

被引：113

作者：

Bozdag-Duendar, Oya ^{[1
]}

Oezgen, Oezen

Mentese, Arzu

Altanlar, Nurten

Atli, Onur

Kendi, Engin

Ertan, Rahmiye

机构：

[1] Ankara Univ, Fac Pharm, Dept Pharmaceut Chem, TR-06100 Ankara, Turkey

[2] Hacettepe Univ, Dept Engn Phys, TR-06800 Ankara, Turkey

[3] Ankara Univ, Fac Pharm, Dept Microbiol, TR-06100 Ankara, Turkey

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2007年 / 15卷 / 18期

关键词：

thiazolidine-2,4-diones; thiazole derivatives; antimicrobial activity; single-x-ray structure;

D O I：

10.1016/j.bmc.2007.06.049

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this study, a series of thiazolyl thiazolidine-2,4-dione derivatives (Va-f and Vla-f) were synthesized and evaluated for their antibacterial and antifungal activities against Staphylococcus aureus (ATCC 25923), methicillin resistant S. aureus (MRSA ATCC 43300), methicillin resistant S. aureus (MRSA isolate), and Escherichia coli (ATCC 23556) and C. albicans (ATCC10145). All the compounds were found active against used microorganisms. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：6012 / 6017

页数：6

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