Antioxidant and Antiacetylcholinesterase Activities of Some Commercial Essential Oils and Their Major Compounds

被引:199
作者
Aazza, Smail [1 ,2 ]
Lyoussi, Badia [2 ]
Miguel, Maria G. [1 ]
机构
[1] Univ Algarve, Plant Biotechnol Res Grp, Dept Chem & Pharm, Inst Biotechnol & Bioengn,Fac Sci & Technol, P-8005139 Faro, Portugal
[2] Univ Sidi Mohamed Ben Abdallah, Lab Physiol Pharmacol Environm Hlth, Fac Sci Dhar El Mehraz, Fes 30000, Morocco
关键词
antiacetylcholinesterase; commercial essential oils; DPPH; reductive potential; TBARS; CHEMICAL-COMPOSITION; ACETYLCHOLINESTERASE; EXTRACTS; INHIBITION; ANTICHOLINESTERASE; CARVACROL; THYMOL; LEAVES; L;
D O I
10.3390/molecules16097672
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
The commercial essential oils of Citrus aurantium L., Cupressus sempervirens L., Eucalyptus globulus Labill., Foeniculum vulgare Mill. and Thymus vulgaris L., isolated by steam distillation by a company of Morocco were evaluated in terms of in vitro antioxidant activity through several methods. In vitro acetylcholinesterase inhibitory activity was also determined. Citrus limon (L.) Burm. f. oil was also studied, but it was obtained by peel expression. The best antioxidant was T. vulgaris oil, independent of the method used, mainly due to the presence of the phenolic monoterpenes thymol and carvacrol, which when studied as single compounds also presented the best activities. Concerning the acetylcholinesterase inhibition activity, E. globulus was the most effective. Nevertheless its main components 1,8-cineole and limonene were not the most active, a feature that corresponded to delta-3-carene.
引用
收藏
页码:7672 / 7690
页数:19
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