Exploitation of perfluorophenyl-phenyl interactions for achieving difficult macrocyclizations by using ring-closing metathesis

被引：49

作者：

El-Azizi, Y ^{[1
]}

Schmitzer, A ^{[1
]}

Collins, SK ^{[1
]}

机构：

[1] Univ Montreal, Dept Chem, Montreal, PQ H3C 3J7, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 06期

关键词：

alkene metathesis; cyclophanes; macrocyclization; perfluoroarenes; quadrupolar interactions;

D O I：

10.1002/anie.200503112

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Correct orientation: Macrocyclic paracyclophanes of multiple ring sizes and diverse functionality are prepared byolefin metathesis (see scheme for an example), through the exploitation of solution-phase quadrupolar interactions between the core arene and pendant pentafluoroarene units. This approach reverses the tendency for dimeric products to be formed during macrocyclizations. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：968 / 973

页数：6

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