Corticofugal control of central auditory sensitivity in the big brown bat, Eptesicus fuscus

被引:46
作者
Sun, XD [1 ]
Chen, QC [1 ]
Jen, PHS [1 ]
机构
[1] UNIV MISSOURI,DIV BIOL SCI,COLUMBIA,MO 65211
关键词
bats; corticofugal regulation; spatial sensitivity; inferior colliculus;
D O I
10.1016/0304-3940(96)12788-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Using bats as a model auditory system, we studied corticofugal control of auditory sensitivity of neurons in the inferior colliculus. We demonstrate for the first time that the corticocollicular pathway continuously regulates acoustic signal processing in the inferior colliculus by increasing the threshold, reducing the auditory spatial response area, and sharpening the frequency tuning curve of recorded inferior collicular neurons. Regulation of auditory sensitivity of recorded inferior collicular neurons was observed when the corticocollicular pathway was activated by electrical stimulation in the auditory cortex. The effect of this corticofugal regulation of auditory sensitivity in inferior collicular neurons can also be produced by ionophoretical application of GABA to the collicular recording site. This regulation of ascending acoustic information by commands originating from higher brain centers may provide the bat with a mechanism to actively control acoustic signal processing and thus optimize acoustic signal analysis.
引用
收藏
页码:131 / 134
页数:4
相关论文
共 17 条
[1]   THE NEOCORTICAL PROJECTION TO THE INFERIOR COLLICULUS IN THE ALBINO-RAT [J].
FAYELUND, H .
ANATOMY AND EMBRYOLOGY, 1985, 173 (01) :53-70
[2]  
FEX J, 1962, ACTA PHYSIOL SC S189, V55, P5
[3]   A TUNGSTEN-IN-GLASS IONTOPHORESIS ASSEMBLY FOR STUDYING INPUT-OUTPUT RELATIONSHIPS IN CENTRAL NEURONS [J].
GODWIN, DW .
JOURNAL OF NEUROSCIENCE METHODS, 1993, 49 (03) :211-223
[4]   EFFECTS OF ELECTRICAL-STIMULATION OF EFFERENT OLIVOCOCHLEAR NEURONS ON CAT AUDITORY-NERVE FIBERS .1. RATE-LEVEL FUNCTIONS [J].
GUINAN, JJ ;
GIFFORD, ML .
HEARING RESEARCH, 1988, 33 (02) :97-113
[5]  
HARVEY DC, 1980, ELECTROEN CLIN NEURO, V48, P249
[6]  
HEFTI BJ, 1995, NEUR ABSTR, V21, P674
[7]   AUDITORY SPACE REPRESENTATION IN THE INFERIOR COLLICULUS OF THE FM BAT, EPTESICUS-FUSCUS [J].
JEN, PHS ;
SUN, XD ;
CHEN, DM ;
TENG, HB .
BRAIN RESEARCH, 1987, 419 (1-2) :7-18
[8]   AUDITORY PHYSIOLOGICAL-PROPERTIES OF THE NEURONS IN THE INFERIOR COLLICULUS OF THE BIG BROWN BAT, EPTESICUS-FUSCUS [J].
JEN, PHS ;
SCHLEGEL, PA .
JOURNAL OF COMPARATIVE PHYSIOLOGY, 1982, 147 (03) :351-363
[9]  
JEN PHS, 1995, NERVOUS SYSTEM BEHAV, P300
[10]  
KNUDSEN EI, 1978, SCIENCE, V202, P778, DOI 10.1126/science.715444