Verbenachalcone, a novel dimeric dihydrochalcone with potentiating activity on nerve growth factor-action from Verbena littoralis

被引：50

作者：

Li, YS ^{[1
]}

Matsunaga, K ^{[1
]}

Kato, R ^{[1
]}

Ohizumi, Y ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Dept Pharmaceut Mol Biol, Aoba Ku, Sendai, Miyagi 9808578, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 06期

关键词：

D O I：

10.1021/np000602w

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A novel dimeric dihydrochalcone, verbenachalcone (1), was isolated from the aerial parts of Verbena littoralis. Its structure was elucidated, on the basis of spectral data interpretation, as 4.2 ' ,4 ' ,2 ' ' ' ,4 ' ' '- pentahydroxy-3 " -methoxy-3-O-4 " -tetrahydrobichalcone. This compound caused a significant enhancement of nerve growth factor-mediated neurite outgrowth from PC12D cells.

引用

页码：806 / 808

页数：3

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