Scabronine A, a novel diterpenoid having potent inductive activity of the nerve growth factor synthesis, isolated from the mushroom, Sarcodon scabrosus

被引：73

作者：

Ohta, T ^{[1
]}

Kita, T

Kobayashi, N

Obara, Y

Nakahata, N

Ohizumi, Y

Takaya, Y

Oshima, Y

机构：

[1] Kanazawa Univ, Fac Pharmaceut Sci, Dept Pharmacognosy & Nat Prod Chem, Kanazawa 9200934, Japan

[2] Tohoku Univ, Fac Pharmaceut Sci, Dept Pharmaceut Mol Biol, Aoba Ku, Sendai, Miyagi 9808578, Japan

[3] Tohoku Univ, Fac Pharmaceut Sci, Dept Pharmacognosy, Aoba Ku, Sendai, Miyagi 9808578, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 34期

关键词：

carboxylic acids and derivatives; fungi; stereochemistry; terpenes and terpenoids;

D O I：

10.1016/S0040-4039(98)01282-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel diterpenoid, scabronine A, having strong inductive activity of the nerve growth factor synthesis was isolated from the fruit body of the mushroom, Sarcodon scabrosus (Fr.) Karat. The stereostructure of scabronine A (1) was elucidated on the basis of the spectroscopic analysis of natural scabronine A and its derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：6229 / 6232

页数：4

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