STIMULATION OF NERVE GROWTH-FACTOR PRODUCTION BY DITERPENOIDS ISOLATED FROM PLANTS OF EUPHORBIA SPECIES

被引：19

作者：

YAMAGUCHI, K ^{[1
]}

UEMURA, D ^{[1
]}

TSUJI, T ^{[1
]}

KONDO, K ^{[1
]}

机构：

[1] SAGAMI CHEM RES CTR, SAGAMIHARA, KANAGAWA 229, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1994年 / 58卷 / 09期

关键词：

D O I：

10.1271/bbb.58.1749

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Kansuinin A, ingenol triacetate, and jolkinolide B, diterpenoids isolated from Euphorbia, were found to be potent inducers of nerve growth factor production in L-M cells. Each of these compounds has unique characteristics in the potency of the activity and the range of effective dose. Kansuinin A had the strongest activity, ingenol triacetate had,vide-range activity, and jolkinolide B had narrow-range activity.

引用

页码：1749 / 1751

页数：3

共 22 条

[1] AMELIORATION OF CHOLINERGIC NEURON ATROPHY AND SPATIAL MEMORY IMPAIRMENT IN AGED RATS BY NERVE GROWTH-FACTOR [J].