共 22 条
STIMULATION OF NERVE GROWTH-FACTOR PRODUCTION BY DITERPENOIDS ISOLATED FROM PLANTS OF EUPHORBIA SPECIES
被引:19
作者:
YAMAGUCHI, K
[1
]
UEMURA, D
[1
]
TSUJI, T
[1
]
KONDO, K
[1
]
机构:
[1] SAGAMI CHEM RES CTR, SAGAMIHARA, KANAGAWA 229, JAPAN
关键词:
D O I:
10.1271/bbb.58.1749
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Kansuinin A, ingenol triacetate, and jolkinolide B, diterpenoids isolated from Euphorbia, were found to be potent inducers of nerve growth factor production in L-M cells. Each of these compounds has unique characteristics in the potency of the activity and the range of effective dose. Kansuinin A had the strongest activity, ingenol triacetate had,vide-range activity, and jolkinolide B had narrow-range activity.
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页码:1749 / 1751
页数:3
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