Hydrogen sulfide: from the smell of the past to the mediator of the future?

被引:265
作者
Moore, PK
Bhatia, M
Moochhala, S
机构
[1] Natl Univ Singapore, Dept Pharmacol, Cardiovasc Res Grp, Singapore 117597, Singapore
[2] Def Sci & Technol Agcy, Def Med Res Inst, Singapore 117597, Singapore
关键词
D O I
10.1016/j.tips.2003.10.007
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Gases such as nitric oxide and carbon monoxide play important roles both in normal physiology and in disease. In recent years, interest has been directed towards other naturally occurring gases, notably hydrogen sulfide (H2S), which is both a potent vasodilator and a mediator of long-term potentiation in the brain. This article focuses on recent work that suggests a role for H2S, and perhaps other gases, in the CNS and cardiovascular system.
引用
收藏
页码:609 / 611
页数:3
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