Shape-Memory Surface with Dynamically Tunable Nano-Geometry Activated by Body Heat

被引：182

作者：

Ebara, Mitsuhiro ^{[1
]}

Uto, Koichiro ^{[1
]}

Idota, Naokazu ^{[1
]}

Hoffman, John M. ^{[1
]}

Aoyagi, Takao ^{[1
]}

机构：

[1] NIMS, Int Res Ctr Mat Nanoarchitecton MANA, Biomat Unit, Tsukuba, Ibaraki 3050044, Japan

来源：

ADVANCED MATERIALS | 2012年 / 24卷 / 02期

关键词：

shape-memory materials; stimuli-responsive materials; polymeric materials; biomedical applications; LINKED ALIPHATIC POLYESTER; POLYMERS;

D O I：

10.1002/adma.201102181

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Shape-memory surfaces with on-demand, tunable nanopatterns are developed to observe time dependent changes in cell alignment using temperature-responsive poly(Ïμ-caprolactone) (PCL) films. Temporary grooved nanopatterns are easily programmed on the films and triggered to transition quickly to permanent surface patterns by the application of body heat. A time-dependent cytoskeleton remodeling is also observed under biologically relevant conditions. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：273 / 278

页数：6

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