Silica gel/NaHSo4 catalyzed one-pot synthesis of Hantzsch 1,4-dihydropyridines at ambient temperature

被引：127

作者：

Chari, MA ^{[1
]}

Syamasundar, K ^{[1
]}

机构：

[1] JNT Univ, Dept Chem, Kukatpally 500072, Hyderabad, India

来源：

CATALYSIS COMMUNICATIONS | 2005年 / 6卷 / 09期

关键词：

Hantzsch 1,4-dihydropyridines; silica gel supported sodium bisulfate;

D O I：

10.1016/j.catcom.2005.03.010

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An efficient synthesis of various substituted Hantzsch 1,4-dihydropyridines (1,4-DHPs) using silica gel-supported sodium bisulfate as heterogenous catalyst for the first time from an aldehyde, beta-keto ester and ammonium acetate in acetonitrile is described. This novel method consistently has the advantage of excellent yields (75-90%) and short reaction time (5-8 h) at ambient temperature. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：624 / 626

页数：3

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