Chiral bis(N-sulfonylamino)phosphine- and TADDOL-phosphite-oxazoline ligands:: Synthesis and application in asymmetric catalysis

被引：100

作者：

Hilgraf, R ^{[1
]}

Pfaltz, A ^{[1
]}

机构：

[1] Univ Basel, Dept Chem, CH-4056 Basel, Switzerland

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2005年 / 347卷 / 01期

关键词：

asymmetric allylic substitution; asymmetric catalysis; asymmetric hydrogenation; N; P ligands; oxazolines;

D O I：

10.1002/adsc.200404168

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A series of N,P-ligands has been prepared, containing a chiral oxazoline ring and as a second chiral unit a bis(N-sulfonylamino)phosphine group embedded in a diazaphospholidine ring or a cyclic phosphite group derived from TADDOL. These modular ligands are readily synthesized from chiral amino alcohols and chiral 1,2-diamines or TADDOLs. Palladium and iridium complexes derived from these ligands were found to be efficient catalysts for enantioselective allylic alkylation and olefin hydrogenation, respectively.

引用

页码：61 / 77

页数：17