An intriguing effect of lithium perchlorate dispersed on silica gel in the bromination of aromatic compounds by N-bromosuccinimide

被引：35

作者：

Bagheri, M ^{[1
]}

Azizi, N ^{[1
]}

Saidi, M ^{[1
]}

机构：

[1] Sharif Univ Technol, Dept Chem, Tehran, Iran

来源：

CANADIAN JOURNAL OF CHEMISTRY | 2005年 / 83卷 / 02期

关键词：

LP-SiO2; NBS; arenes; electrophilic bromination; regioselectivity;

D O I：

10.1139/V05-001

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient and efficient procedure for electrophilic aromatic bromination has been developed by mixing of N-bromosuccinimide and an aromatic compound at room temperature on the surface of silica gel mixed with solid anhydrous LiClO4. All of the substrates examined underwent clean electrophilic aromatic bromination in reaction times of a few minutes to afford the corresponding bromoarenes under neutral conditions in excellent yield. In the case of thiophenol, no substitution reaction occurred, and the corresponding disulfide was obtained in excellent yield.

引用

页码：146 / 149

页数：4