The σB regulon influences internalization of Staphylococcus aureus by osteoblasts

被引：47

作者：

Nair, SP

Bischoff, M

Senn, MM

Berger-Bächi, B

机构：

[1] UCL, Cellular Microbiol Res Grp, Eastman Dent Inst Oral Hlth Care Sci, London WC1X 8LD, England

[2] Univ Zurich, Inst Med Microbiol, CH-8028 Zurich, Switzerland

来源：

INFECTION AND IMMUNITY | 2003年 / 71卷 / 07期

关键词：

D O I：

10.1128/IAI.71.7.4167-4170.2003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Individual strains of Staphylococcus aureus have different capacities to become internalized by osteoblasts. Here we report that the levels of sigma(B) expressed by S. aureus correlate with the capacity of this bacterium to be internalized by osteoblasts. However, sigma(B) is not essential for internalization and does not necessarily account for the differences in the capacities of strains to be internalized.

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页码：4167 / 4170

页数：4

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