Organic reaction in water. Part 3: Diastereoselectivity in Michael additions of thiophenol to nitro olefins in aqueous media

被引：28

作者：

da Silva, FM ^{[1
]}

Jones, J ^{[1
]}

机构：

[1] Univ Fed Rio de Janeiro, Inst Quim, Dept Quim Organ, BR-21945970 Rio De Janeiro, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2001年 / 12卷 / 02期

关键词：

Michael additions in water; nitro olefins; thio compounds;

D O I：

10.1590/S0103-50532001000200002

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Thiophenol reacts with nitro olefins in aqueous media to give the corresponding nitro-sulfides in 58-95% yield. This procedure results in selective formation of the anti products. In the case of the cyclic nitro olefin 1-nitro-cyclohexene the only product observed was the cis-1-nitro-2-(phenylthio)cyclohexane. This methodology is of interest due to the use of water as solvent, thus minimizing the cost, the operational hazards and environmental pollution.

引用

页码：135 / 137

页数：3

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