Automatic detection of stent struts with thick neointimal growth in intravascular optical coherence tomography image sequences

被引：31

作者：

Xu, Chenyang ^{[1
]}

Schmitt, Joseph M. ^{[1
]}

Akasaka, Takashi ^{[2
]}

Kubo, Takashi ^{[2
]}

Huang, Kun ^{[3
]}

机构：

[1] Lightlab Imaging Inc, Westford, MA 01886 USA

[2] Wakayama Med Univ, Dept Cardiovasc Med, Wakayama, Japan

[3] Ohio State Univ, Dept Biomed Informat, Columbus, OH 43210 USA

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2011年 / 56卷 / 20期

基金：

日本学术振兴会;

关键词：

BALLOON ANGIOPLASTY; PLACEMENT;

D O I：

10.1088/0031-9155/56/20/010

中图分类号：

R318 [生物医学工程];

学科分类号：

100103 [病原生物学];

摘要：

To assist cardiologists investigating neointimal tissue growth on stents during follow-up with optical coherence tomography (OCT), we developed an automatic algorithm to locate deeply buried stent struts and to quantify the restenosis burden. The technique is based on an improved steerable filter for computing the local ridge strength and orientation. It also uses an ellipsoid fitting algorithm and continuity criteria to obtain globally optimal stent localization. The restenosis burden calculations were compared to manual assessment of OCT coronary artery image data obtained from in vivo human clinical studies. Compared to manual assessment by expert readers, the algorithm operated with > 97% accuracy in the measurement of mean and maximum restenosis burden. The results indicated that the technique yielded comparable accuracy in measuring restenosis burden, and significantly reduced user interaction time.

引用

页码：6665 / 6675

页数：11

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