A DNA Nanostructure-based Biomolecular Probe Carrier Platform for Electrochemical Biosensing

被引：513

作者：

Pei, Hao ^{[3
]}

Lu, Na ^{[3
]}

Wen, Yanli ^{[3
]}

Song, Shiping ^{[3
]}

Liu, Yan ^{[1
,2
]}

Yan, Hao ^{[1
,2
]}

Fan, Chunhai ^{[3
]}

机构：

[1] Arizona State Univ, Dept Chem & Biochem, Tempe, AZ 85287 USA

[2] Arizona State Univ, Biodesign Inst, Tempe, AZ USA

[3] Chinese Acad Sci, Shanghai Inst Appl Phys, Phys Biol Lab, Shanghai 201800, Peoples R China

来源：

ADVANCED MATERIALS | 2010年 / 22卷 / 42期

关键词：

SEQUENCE-SPECIFIC DETECTION; CHRONOCOULOMETRIC DNA; FEMTOMOLAR DNA; FOLDING DNA; GOLD; SENSOR; RECOGNITION; DESIGN;

D O I：

10.1002/adma.201002767

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A 3D DNA nanostructure-based sensor platform for DNA detection has been developed. This strategy provides significantly enhanced spatial positioning range and accessibility of the probes on a surface over previously reported DNA sensing architectures. The use of this versatile DNA nanostructure-based detection platform leads to highly sensitive and selective DNA detection in biological fluids and greatly enhanced sequence specificity for SNP typing.

引用

页码：4754 / +

页数：6

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