Circulating matrix metalloproteinase-1 and-3 in patients with an acute coronary syndrome

被引：53

作者：

Inoue, T

Kato, T

Takayanagi, K

Uchida, T

Yaguchi, I

Kamishirado, H

Morooka, S

Yoshimoto, N

机构：

[1] Dokkyo Univ, Sch Med, Koshigaya Hosp, Dept Cardiol, Koshigaya, Saitama 3438555, Japan

[2] Saitama Med Sch, Med Ctr, Dept Internal Med 3, Div Cardiol, Kawagoe, Saitama, Japan

[3] Tokyo Med & Dent Univ, Dept Cardiovasc Med, Tokyo, Japan

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2003年 / 92卷 / 12期

关键词：

D O I：

10.1016/j.amjcard.2003.08.061

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To elucidate the diagnostic value of serum matrix metalloproteinase (MMP) levels, we measured MMP-1 and MMP-3 by a 1-step sandwich enzyme immunoassay. The transcardiac gradients of both MMPs were greater in patients with unstable angina and acute myocardial infarction than in patients with stable effort angina or control patients. Serum MMP levels appear to be a marker of plaque instability in patients with acute coronary syndrome. (C) 2003 by Excerpta Medica, Inc.

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页码：1461 / 1464

页数：4

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