The Many Faces of RNAi

被引：267

作者：

Ketting, Rene F. ^{[1
,2
,3
]}

机构：

[1] Hubrecht Inst KNAW, NL-3584 CT Utrecht, Netherlands

[2] Univ Med Ctr Utrecht, NL-3584 CT Utrecht, Netherlands

[3] Univ Utrecht, Fac Vet Med, Dept Equine Sci, NL-3584 CM Utrecht, Netherlands

来源：

DEVELOPMENTAL CELL | 2011年 / 20卷 / 02期

基金：

欧洲研究理事会;

关键词：

PIWI-INTERACTING RNAS; SMALL INTERFERING RNAS; GERM-CELL DIFFERENTIATION; SELFISH GENETIC ELEMENTS; PRIMARY PIRNA BIOGENESIS; NOVO DNA METHYLATION; C-ELEGANS; ENDOGENOUS SIRNAS; ARGININE METHYLATION; ARGONAUTE PROTEINS;

D O I：

10.1016/j.devcel.2011.01.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Small non-coding RNAs, through association with Argonaute protein family members, have a variety of functions during the development of an organism. Although there is increased mechanistic understanding of the RNA interference (RNAi) pathways surrounding these small RNAs, how their effects are modulated by subcellular compartmentalization and cross-pathway functional interactions is only beginning to be explored. This review examines the current understanding of these aspects of RNAi pathways and the biological functions of these pathways.

引用

页码：148 / 161

页数：14

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