Beyond Tsg101: the role of Alix in 'ESCRTing' HIV-1

被引：137

作者：

Fujii, Ken

Hurley, James H.

Freed, Eric O. ^{[1
]}

机构：

[1] NCI, HIV Drug Resistance Program, Virus Cell Interact Sect, Frederick, MD 21702 USA

[2] NIH, Natl Inst Diabet & Digest & Kidney Dis, Mol Biol Lab, Bethesda, MD 20892 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2007年 / 5卷 / 12期

关键词：

D O I：

10.1038/nrmicro1790

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The limited coding capacity of retroviral genomes forces these viruses to rely heavily on the host-cell machinery for their replication. This phenomenon is particularly well illustrated by the interaction between retroviruses and components of the endosomal budding machinery that occurs during virus release. Here, we focus on the use of host-cell factors during HIV-1 budding and highlight recent progress in our understanding of the role of one such factor, Alix, in both viral and cellular membrane budding and fission events.

引用

页码：912 / 916

页数：5

共 41 条

[31] Equine infectious anemia virus utilizes a YXXL motif within the late assembly domain of the Gag p9 protein
Puffer, BA
Parent, LJ
Wills, JW
Montelaro, RC
[J]. JOURNAL OF VIROLOGY, 1997, 71 (09) : 6541 - 6546
[32] Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities
Schmidt, MHH
Dikic, I
Bögler, O
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (05) : 3414 - 3425
[33] AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding
Strack, B
Calistri, A
Craig, S
Popova, E
Göttlinger, HG
[J]. CELL, 2003, 114 (06) : 689 - 699
[34] SWANSTROM R, 1997, SYNTHESIS ASSEMBLY P, P263
[35] Alix, a protein regulating endosomal trafficking, is involved in neuronal death
Trioulier, Y
Torch, S
Blot, B
Cristina, N
Chatellard-Causse, C
Verna, JM
Sadoul, R
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (03) : 2046 - 2052
[36] Potent rescue of human immunodeficiency virus type 1 late domain mutants by ALIX/AIP1 depends on its CHMP4 binding site
Usami, Yoshiko
Popov, Sergei
Gottlinger, Heinrich G.
[J]. JOURNAL OF VIROLOGY, 2007, 81 (12) : 6614 - 6622
[37] Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55Gag
VerPlank, L
Bouamr, F
LaGrassa, TJ
Agresta, B
Kikonyogo, A
Leis, J
Carter, CA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (14) : 7724 - 7729
[38] Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction
Vito, P
Pellegrini, L
Guiet, C
D'Adamio, L
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (03) : 1533 - 1540
[39] The protein network of HIV budding
von Schwedler, UK
Stuchell, M
Müller, B
Ward, DM
Chung, HY
Morita, E
Wang, HE
Davis, T
He, GP
Cimbora, DM
Scott, A
Kräusslich, HG
Kaplan, J
Morham, SG
Sundquist, WI
[J]. CELL, 2003, 114 (06) : 701 - 713
[40] HIV-1 buds predominantly at the plasma membrane of primary human macrophages
Welsch, Sonja
Keppler, Oliver T.
Habermann, Anja
Allespach, Ina
Krijnse-Locker, Jacomine
Kraeusslich, Hans-Georg
[J]. PLOS PATHOGENS, 2007, 3 (03)

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