Dystrophic Epidermolysis Bullosa: Pathogenesis and Clinical Features

被引：80

作者：

Bruckner-Tuderman, Leena ^{[1
]}

机构：

[1] Univ Med Ctr Freiburg, Dept Dermatol, D-79104 Freiburg, Germany

来源：

DERMATOLOGIC CLINICS | 2010年 / 28卷 / 01期

关键词：

Blistering; Scarring; Dermal-epidermal junction; Anchoring fibrils; GLYCINE SUBSTITUTION MUTATIONS; VII COLLAGEN; ANCHORING FIBRILS; COL7A1; MUTATIONS; SKIN; PHENOTYPE; PRURIGINOSA; THERAPY; MODEL; DERMOLYSIS;

D O I：

10.1016/j.det.2009.10.020

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Dystrophic epidermolysis bullosa (DEB) is relatively well understood. Potential therapies are in development. This article describes the pathogenesis and clinical features of DEB. It also describes therapeutic options and the future of molecular therapies.

引用

页码：107 / +

页数：9

共 32 条

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