Distal sensory axonopathy after sarin intoxication

被引：24

作者：

Himuro, K

Murayama, S

Nishiyama, K

Shinoe, T

Iwase, H

Nagao, M

Takatori, T

Kanazawa, I

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Neurol, Div Neurosci, Tokyo, Japan

[2] Univ Tokyo, Grad Sch Med, Dept Forens Med, Tokyo, Japan

来源：

NEUROLOGY | 1998年 / 51卷 / 04期

关键词：

D O I：

10.1212/WNL.51.4.1195

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 51-year-old man inhaled sarin during a terrorist attack on the Tokyo subway system and died 15 months later. Neuropathologic examination revealed marked nerve fiber decrease in the sural nerve, moderate nerve fiber loss in the sciatic nerve, and unremarkable dorsal root ganglia, dorsal roots, and posterior column of the spinal cord. This pathology is consistent with dying-back degeneration of the peripheral nervous system and could represent a late sequela of sarin intoxication.

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页码：1195 / 1197

页数：3

相关论文

共 10 条

[1] The systemic nervous affinity of triorthocresyl phosphate (Jamaica ginger palsy) [J].

Aring, CD .

BRAIN, 1942, 65 :34-47

[2] THE TOXIC EFFECTS OF TRI-ORTHO-CRESYL PHOSPHATE ON THE NERVOUS SYSTEM - AN EXPERIMENTAL STUDY IN HENS [J].

CAVANAGH, JB .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1954, 17 (03) :163-172

[3]

DYCK PJ, 1993, PERIPHERAL NEUROPATH, P514

[4] THE DELAYED NEUROPATHIC EFFECTS OF NERVE AGENTS AND SOME OTHER ORGANO-PHOSPHORUS COMPOUNDS [J].

GORDON, JJ ;

INNS, RH ;

JOHNSON, MK ;

LEADBEATER, L ;

MAIDMENT, MP ;

UPSHALL, DG ;

COOPER, GH ;

RICKARD, RL .

ARCHIVES OF TOXICOLOGY, 1983, 52 (02) :71-82

[5] DELAYED NEUROTOXIC EFFECT OF SARIN IN MICE AFTER REPEATED INHALATION EXPOSURE [J].

HUSAIN, K ;

VIJAYARAGHAVAN, R ;

PANT, SC ;

RAZA, SK ;

PANDEY, KS .

JOURNAL OF APPLIED TOXICOLOGY, 1993, 13 (02) :143-145

[6]

ISHIYAMA I, 1996, NIPPON HOIGAKU ZASSH, V50, P220

[7] Neuropathy target esterase (NTE) and organophosphorus-induced delayed polyneuropathy (OPIDP): Recent advances [J].

Johnson, MK ;

Glynn, P .

TOXICOLOGY LETTERS, 1995, 82-3 :459-463

[8] Phenyl valerate esterases other than neuropathy target esterase and the promotion of organophosphate polyneuropathy [J].

Milatovic, D ;

Moretto, A ;

Osman, KA ;

Lotti, M .

CHEMICAL RESEARCH IN TOXICOLOGY, 1997, 10 (09) :1045-1048

[9] Sarin poisoning on Tokyo subway [J].

Ohbu, S ;

Yamashina, A ;

Takasu, N ;

Yamaguchi, T ;

Murai, T ;

Nakano, K ;

Matsui, Y ;

Mikami, R ;

Sakurai, K ;

Hinohara, S .

SOUTHERN MEDICAL JOURNAL, 1997, 90 (06) :587-593

[10]

YUASA R, 1970, RINSHO SHINKEIGAKU, V10, P170