Influence of repetitive transcranial magnetic stimulation on special symptoms in depressed patients

被引:10
作者
Hoeppner, Jacqueline [1 ]
Berger, Christoph [1 ]
Walter, Uwe [2 ]
Padberg, Frank [3 ]
Buchmann, Johannes [4 ]
Herwig, Uwe [5 ]
Domes, Gregor [6 ]
机构
[1] Univ Rostock, Ctr Nervous Dis, Dept Psychiat & Psychotherapy, Rostock, Germany
[2] Univ Rostock, Ctr Nervous Dis, Dept Neurol, Rostock, Germany
[3] Univ Munich, Dept Psychiat & Psychotherapy, Munich, Germany
[4] Univ Rostock, Ctr Nervous Dis, Dept Psychiat Neurol Psychosomat & Psychotherapy, Rostock, Germany
[5] Psychiat Univ Hosp Zurich, Zurich, Switzerland
[6] Univ Freiburg, Dept Psychol, Lab Biol & Personal Psychol, Freiburg, Germany
关键词
DORSOLATERAL PREFRONTAL CORTEX; PARKINSONS-DISEASE; SUBSTANTIA-NIGRA; MAJOR DEPRESSION; DOPAMINE RELEASE; INCREASED RISK; SONOGRAPHY; RETARDATION; DISORDER; HYPERECHOGENICITY;
D O I
10.3233/RNN-2010-0557
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Since various studies, including multi-centre studies, investigating the effect of repetitive transcranial magnetic stimulation (rTMS) in depression have shown different results, it is now important to research, which symptoms of depression are most responsive to this kind of non-invasive brain stimulation. Furthermore, an increasing interest of rTMS as a potential tool for treatment of neurological and psychiatric disorders should be recorded. Therefore, it is critical to investigate dopaminergic functional interactions in the prefrontal cortex, and in particular, the effect of dorsolateral prefrontal cortex stimulation on clinical symptoms depending on dopaminergic concentrations in various brain regions. This short review summarizes important preliminary data, which focus on the symptom-oriented effects of rTMS in depression.
引用
收藏
页码:577 / 585
页数:9
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