Cytokine expression in the mouse brain in response to immune activation by Corynebacterium parvum

被引：19

作者：

Sheng, WS

Hu, S

Ding, JM

Chao, CC

Peterson, PK

机构：

[1] Minneapolis Med Res Fdn, Inst Brain & Immune Disorders, NeuroImmunol Lab, Minneapolis, MN 55404 USA

[2] Univ Minnesota, Sch Med, Minneapolis, MN 55404 USA

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2001年 / 8卷 / 02期

关键词：

D O I：

10.1128/CDLI.8.2.446-448.2001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cytokine expression in the brain has been suggested to mediate various sickness behaviors. Here we report that intraperitoneal injection of a Corynebacterium parvum antigen in C57BL/6 mice was followed by prolonged upregulation of cytokines in the cerebral cortex and subcortical structures in a time course that coincided with reduced spontaneous running activity.

引用

页码：446 / 448

页数：3