Antimicrobial susceptibility and macrolide resistance inducibility of Streptococcus pneumoniae carrying erm(A), erm(B), or mef(A)

被引：24

作者：

Syrogiannopoulos, GA

Grivea, IN

Ednie, LM

Bozdogan, B

Katopodis, GD

Beratis, NG

Davies, TA

Appelbaum, PC

机构：

[1] Univ Patras, Sch Med, Gen Univ Hosp, Dept Pediat, GR-26110 Patras, Greece

[2] Penn State Univ, Milton S Hershey Med Ctr, Dept Pathol, Hershey, PA 17033 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 08期

关键词：

D O I：

10.1128/AAC.47.8.2699-2702.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Erythromycin-resistant Streptococcus pneumoniae isolates from young carriers were tested for their antimicrobial susceptibility; additionally, inducibility of macrolide and clindamycin resistance was investigated in pneumococci carrying erm(A), erm(B), or mef(A). Of 125 strains tested, 101 (81%) were multidrug resistant. Different levels of induction were observed with erythromycin, miocamycin, and clindamycin in erm (B) strains; however, in erm(A) strains only erythromycin was an inducer. Induction did not affect macrolide MICs in mef(A) strains.

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页码：2699 / 2702

页数：4

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