Flavonol glycosides and steroidal saponins from the leaves of Cestrum nocturnum and their cytotoxicity

被引：42

作者：

Mimaki, Y

Watanabe, K

Ando, Y

Sakuma, C

Sashida, Y

Furuya, S

Sakagami, H

机构：

[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Lab Med Plant Sci, Hachioji, Tokyo 1920392, Japan

[2] Meikai Univ, Sch Dent, Dept Dent Pharmacol, Sakado, Saitama 3500283, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 01期

关键词：

D O I：

10.1021/np0003701

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical analysis of the leaves of Cestrum nocturnum (Solanaceae) resulted in the isolation of two new flavonol glycosides (1, 2) and seven steroidal saponins (3-9), including four new ones (4, 6, 7, and 9). The structures of the new compounds were determined by spectroscopic analysis, including 2D NMR data, and the results of hydrolytic cleavage. Cytotoxic activities of the isolated compounds against human oral squamous cell carcinoma-(HSC-2) cells and normal human gingival fibroblasts are reported.

引用

页码：17 / 22

页数：6