Biosynthesis of tetronasin .7. Preparation of structural analogues of the tetraketide biosynthetic precursor to tetronasin

被引:13
作者
Less, SL
Leadlay, PF
Dutton, CJ
Staunton, J
机构
[1] UNIV CAMBRIDGE,DEPT CHEM,CAMBRIDGE CB2 1EW,ENGLAND
[2] PFIZER LTD,DIV CENT RES,SANDWICH CT13 9NJ,KENT,ENGLAND
[3] UNIV CAMBRIDGE,DEPT BIOCHEM,CAMBRIDGE CB2 1QW,ENGLAND
关键词
D O I
10.1016/0040-4039(96)00601-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The preparation of three structural analogues of the putative tetraketide biosynthetic precursor (2) of the acyl tetronic acid ionophore tetronasin, as N-acetylcysteamine thioesters (3), (4) and (5) is described. Two examples are F-19-labelled. Copyright (C) 1996 Elsevier Science Ltd
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页码:3519 / 3520
页数:2
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