Tandem hydroformylation-hydrazone formation-Fischer indole synthesis: a novel approach to tryptamides

被引:45
作者
Schmidt, AM [1 ]
Eilbracht, P [1 ]
机构
[1] Univ Dortmund, Fachbereich Chem, D-44227 Dortmund, Germany
关键词
D O I
10.1039/b503396a
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel one-pot synthesis of indole systems via tandem hydroformylation-hydrazone formation-Fischer indolization starting from allylic amides and aryl hydrazines is described. This tandem procedure directly leads to biologically interesting tryptamides and analogues.
引用
收藏
页码:2333 / 2343
页数:11
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