Highly selective synthesis of hydrazones and indoles from olefins

被引：30

作者：

Ahmed, M ^{[1
]}

Jackstell, R ^{[1
]}

Seayad, AM ^{[1
]}

Klein, H ^{[1
]}

Beller, M ^{[1
]}

机构：

[1] Univ Rostock eV, IfOK, Leibniz Inst Organ Katalyse, D-18055 Rostock, Germany

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 04期

关键词：

D O I：

10.1016/j.tetlet.2003.11.044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of aliphatic olefins with synthesis gas and hydrazines in the presence of rhodium phosphine catalysts leads directly to the corresponding hydrazones. Applying Iphos as ligand good to excellent yields and high chemo- and regioselectivities were obtained in toluene under mild conditions. In case of aromatic hydrazines in situ Fischer indole synthesis can be combined with the new hydrazone preparation to give substituted indoles directly from olefins. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：869 / 873

页数：5

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