Substrate-directed diastereoselective hydroaminomethylation of methallylic alcohols

被引：39

作者：

Breit, B ^{[1
]}

机构：

[1] Philipps Univ Marburg, Fachbereich Chem, D-35043 Marburg, Germany

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 29期

关键词：

hydroformylation; catalysis; stereocontrol; asymmetric reactions; asymmetric synthesis;

D O I：

10.1016/S0040-4039(98)01038-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substrate directed diastereoselective hydroaminomethylation of methallylic alcohols has been achieved with the aid of the substrate bound catalyst directing o-DPPB-group (o-DPPB = ortho-diphenylphosphanyl benzoate). The amines 3-7, 10, 11 have been obtained in fair to good yields in diastereomer ratios greater than or equal to 94:6 (syn : anti). (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5163 / 5166

页数：4

共 29 条

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