Chemo-enzymatic preparations of (R)- and (S)-3-iodocyclohex-2-en-1-yl acetate

被引：8

作者：

Barnier, JP ^{[1
]}

Blanco, L ^{[1
]}

机构：

[1] Univ Paris 11, Lab Carbocycles, CNRS, Inst Chim Mol & Mat Orsay, F-91405 Orsay, France

来源：

SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 14期

关键词：

D O I：

10.1081/SCC-120021839

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Kinetic resolutions by lipase-catalyzed transesterification with 3-iodocyclohex-2-en-1-ol or 3-iodocyclohex-2-en-1-yl acetate followed by inversion of the chirality of the optically active alcohol without separation from the acetate have allowed the preparation of (R)- and (S)-3-iodocyclohex-2-en-1-yl acetate with more than 70% yield and more than 85% ee.

引用

页码：2487 / 2496

页数：10

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