Gene therapy for breast cancer

被引:11
作者
Boxhorn, HKE [1 ]
Eck, SL [1 ]
机构
[1] Univ Penn, Med Ctr, Dept Med, Div Hematol & Oncol, Philadelphia, PA 19104 USA
关键词
D O I
10.1016/S0889-8588(05)70014-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Gene therapy for breast cancer is still in the very early stages of development. Many of the molecular strategics that have been proposed are also being developed for other cancers. Their application to breast cancer, however, needs to address several issues specific to this disease such as the widespread nature of metastases the indolent growth of the tumor cells, and the production by the tumor of immunosuppressive agents. Nonetheless, these approaches appear promising, particularly those that employ a combination of strategies. Gene therapies that affect the biology of breast cancer cells or regulate host immun mechanisms have bren most successful and may be paired with existing therapies for breast cancer.
引用
收藏
页码:665 / +
页数:12
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