In My Opinion: Serum Albumin Should be Maintained During Neurocritical Care

被引:8
作者
Powner, David J. [1 ,2 ]
机构
[1] Univ Texas Hlth Sci Ctr Houston Med Sch, Dept Neurosurg & Internal Med, Houston, TX 77030 USA
[2] Vivian L Smith Ctr Neurol Res, Houston, TX USA
关键词
Serum albumin; Brain injuries; Brain infarction; Cerebrovascular accident; TRAUMATIC BRAIN-INJURY; ACUTE ISCHEMIC-STROKE; COLLOID ONCOTIC THERAPY; C-REACTIVE PROTEIN; SEVERE HEAD-INJURY; PREOPERATIVE HYPOALBUMINEMIA; HOSPITALIZED-PATIENTS; PROGNOSTIC VALUE; CRITICALLY-ILL; RISK-FACTOR;
D O I
10.1007/s12028-011-9513-z
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Hypoalbuminemia is common among critically ill/injured patients and is strongly associated with increased morbidity and mortality in the patients with and without neurological conditions. Normal serum albumin is important as the primary intravascular antioxidant, in transporting a variety of hormones, medications and electrolytes, in providing colloid osmotic pressure during trans-compartmental fluid movement, in enhancing organ and tissue blood flow, and in supporting acid-base balance. Studies of albumin administration during intravascular resuscitation have not addressed potential longer term benefits to sustaining serum albumin concentrations during critical care. Evidence for such benefit is present although additional prospective studies are needed.
引用
收藏
页码:482 / 488
页数:7
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