Stereoselective synthesis of meso- and cis-2,6-diarylpiperidin-4-ones catalyzed by L-proline

被引：10

作者：

Aznar, Fernando ^{[1
]}

Garcia, Ana-Belen ^{[1
]}

Quinones, Noelia ^{[1
]}

Cabal, Maria-Paz ^{[1
]}

机构：

[1] Univ Oviedo, Unidad Asociada CSIC, Inst Univ Quim Organometal Enr Moles, E-33006 Oviedo, Spain

来源：

SYNTHESIS-STUTTGART | 2008年 / 3卷 / 03期

关键词：

2,6-diarylpiperidin-4-ones; organocatalysis; L-proline; aza-Diels-Alder; nitrogen heterocycles;

D O I：

10.1055/s-2007-990814

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient stereoselective preparation of meso- and cis-2,6-diarylpiperidin-4-ones has been developed by aza-Diels-Alder reaction catalyzed by L-proline from simple and commercially available starting materials.

引用

页码：479 / 484

页数：6

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