Cell biology of the intracellular infection by Legionella pneumophila

被引：55

作者：

Molmeret, M

Bitar, DM

Han, LH

Abu Kwaik, Y ^{[1
]}

机构：

[1] Univ Louisville, Coll Med, Dept Microbiol & Immunol, Louisville, KY 40292 USA

[2] Univ Kentucky, Coll Med, Dept Microbiol & Immunol, Lexington, KY 40536 USA

[3] Al Quds Univ, Fac Med, Dept Med Microbiol & Immunol, IL-19356 Jerusalem, Israel

[4] Shandong Univ, Coll Med, Dept Microbiol & Immunol, Shandong 250012, Peoples R China

来源：

MICROBES AND INFECTION | 2004年 / 6卷 / 01期

关键词：

intracellular; dot/icm; secretion;

D O I：

10.1016/j.micinf.2003.11.004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Legionella pneumophila has become a paradigm for facultative intracellular pathogens that modulate biogenesis of their phagosomes into replicative niches. The ability to alter host cell biology and tailor it into a hospitable host for intracellular proliferation is at the crux of the mechanism of pathogenesis of Legionnaires' disease. (C) 2003 Elsevier SAS. All rights reserved.

引用

收藏

页码：129 / 139

页数：11

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