Preparation of fine W/O/W emulsion through membrane filtration of coarse W/O/W emulsion and disappearance of the inclusion of outer phase solution

被引：42

作者：

Shima, M ^{[1
]}

Kobayashi, Y ^{[1
]}

Fujii, T ^{[1
]}

Tanaka, M ^{[1
]}

Kimura, Y ^{[1
]}

Adachi, S ^{[1
]}

Matsuno, R ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Agr, Div Food Sci & Biotechnol, Sakyo Ku, Kyoto 6068502, Japan

来源：

FOOD HYDROCOLLOIDS | 2004年 / 18卷 / 01期

基金：

日本学术振兴会;

关键词：

bioactive compound; functional food; membrane emulsification; rotor/stator homogenizer; fine water-in-oil-in-water emulsion;

D O I：

10.1016/S0268-005X(03)00042-0

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A water-in-oil-in-water (W/O/W) emulsion was prepared as a carrier system for the daily uptake of a bioactive compound using decaglycerol monolaurate and hexaglyceryl condensed ricinolate as hydrophilic and lipophilic surfactants, respectively. 1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt (PTSA) was used as a hydrophilic model compound of a bioactive substance. Membrane filtration of a coarse W/O/W emulsion prepared with a rotor/stator homogenizer produced a fine emulsion which had a mean oil-droplet diameter of < 1 mum. The emulsions were stable for I week at 4 degreesC. The encapsulation efficiency of PTSA was > 90%. Microscopic observations revealed that the fluorescent material in the outer-phase solution was included into the oil phase during rotor/stator homogenization. It was suggested that because the rotor/stator homogenizer was used to produce both O/W and W/O/W emulsions, some part of the outer phase solution would be included in the oil phase during the second homogenization. The fluorescence shown in the oil droplets of the coarse W/O/W emulsion was diminished after membrane emulsification. This phenomenon suggested that the included outer-phase solution was released to the outer-phase solution from the interior of the W/O/W oil droplets during the membrane emulsification. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：61 / 70

页数：10

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