Evaluation of gas chromatography-tandem quadrupole mass spectrometry for the determination of organochlorine pesticides in fats and oils

被引:81
作者
Patel, K
Fussell, RJ [1 ]
Hetmanski, M
Goodall, DM
Keely, BJ
机构
[1] Cent Sci Lab, York YO14 1LZ, N Yorkshire, England
[2] Univ York, York YO10 5DD, N Yorkshire, England
关键词
tandem quadrupole mass spectrometry; gas chromatography; organochlorine pesticides; fats and oils;
D O I
10.1016/j.chroma.2005.01.040
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A gas chromatography-tandem quadrupole mass spectrometry multi-residue method for the analysis of 19 organochlorine pesticides in fats and oils has been developed. Gel permeation chromatography was employed to remove lipid material prior to GC-MS/MS analysis. Average recoveries of the pesticides spiked at 10 and 50 mu g kg(-1) into fish oil, pork fat, olive oil and hydrogenated vegetable oil were typically in the range 70-110% with relative standard deviations generally less than 10%. Calculated limits of detection are between 0.1 and 2.0 mu g kg(-1) and results obtained for the analysis of proficiency test materials are in good agreement with assigned values. The higher selectivity of the GC-MS/MS compared to electron capture detection and GC-MS in selective ion monitoring mode allowed unambiguous identification and confirmation of all the target pesticides at low mu g kg(-1) levels in fats and oils in a single analysis. Crown Copyright (c) 2005 Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:289 / 296
页数:8
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