Lung cancer in never smokers - a different disease

被引：1196

作者：

Sun, Sophie

Schiller, Joan H.

Gazdar, Adi F. ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Hamon Ctr Therapeut Oncol Res, Dallas, TX 75230 USA

[2] Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75230 USA

[3] Univ Texas, SW Med Ctr, Div Haematol & Oncol, Dallas, TX 75230 USA

[4] Univ Texas, SW Med Ctr, Dept Internal Med, Dallas, TX 75230 USA

来源：

NATURE REVIEWS CANCER | 2007年 / 7卷 / 10期

关键词：

D O I：

10.1038/nrc2190

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Although most lung cancers are a result of smoking, approximately 25% of lung cancer cases worldwide are not attributable to tobacco use, accounting for over 300,000 deaths each year. Striking differences in the epidemiological, clinical and molecular characteristics of lung cancers arising in never smokers versus smokers have been identified, suggesting that they are separate entities. This Review summarizes our current knowledge of this unique and poorly understood disease.

引用

页码：778 / 790

页数：13

共 166 条

[1]

Ahrendt SA, 2001, CANCER, V92, P1525, DOI 10.1002/1097-0142(20010915)92:6<1525::AID-CNCR1478>3.0.CO

[2]

2-H

[3] Epidemiology of lung cancer: Looking to the future [J].

Alberg, AJ ;

Brock, MV ;

Samet, JM .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (14) :3175-3185

[4]

[Anonymous], HLTH CONS INV EXP TO

[5]

BADAR F, 2006, J CANC PREV, V7, P245

[6] A major lung cancer susceptibility locus maps to chromosome 6q23-25 [J].

Bailey-Wilson, JE ;

Amos, CI ;

Pinney, SM ;

Petersen, GM ;

de Andrade, M ;

Wiest, JS ;

Fain, P ;

Schwartz, AG ;

You, M ;

Franklin, W ;

Klein, C ;

Gazdar, A ;

Rothschild, H ;

Mandal, D ;

Coons, T ;

Slusser, J ;

Lee, J ;

Gaba, C ;

Kupert, E ;

Perez, A ;

Zhou, X ;

Zeng, D ;

Liu, Q ;

Zhang, Q ;

Seminara, D ;

Minna, J ;

Anderson, MW .

AMERICAN JOURNAL OF HUMAN GENETICS, 2004, 75 (03) :460-474

[7]

*BEIR, 1999, REP HLTH EFF EXP IND

[8] Estrogen replacement therapy and risk of lung cancer [J].

Blackman, JA ;

Coogan, PF ;

Rosenberg, L ;

Strom, BL ;

Zauber, AG ;

Palmer, JR ;

Langenberg, P ;

Shapiro, S .

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2002, 11 (07) :561-567

[9] Epidermal growth factor receptor mutation in lung cancer are linked to bronchioloalveolar differentiation [J].

Blons, Helene ;

Cote, Jean-Francois ;

Le Corre, Delphine ;

Riquet, Marc ;

Fabre-Guilevin, Elisabeth ;

Laurent-Puig, Pierre ;

Danel, Claire .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2006, 30 (10) :1309-1315

[10] Incidence of lung cancer in a large cohort of non-smoking men from Sweden [J].

Boffetta, P ;

Järvholm, B ;

Brennan, P ;

Nyrén, O .

INTERNATIONAL JOURNAL OF CANCER, 2001, 94 (04) :591-593

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