Lung cancer in never smokers - a different disease

被引：1196

作者：

Sun, Sophie

Schiller, Joan H.

Gazdar, Adi F. ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Hamon Ctr Therapeut Oncol Res, Dallas, TX 75230 USA

[2] Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75230 USA

[3] Univ Texas, SW Med Ctr, Div Haematol & Oncol, Dallas, TX 75230 USA

[4] Univ Texas, SW Med Ctr, Dept Internal Med, Dallas, TX 75230 USA

来源：

NATURE REVIEWS CANCER | 2007年 / 7卷 / 10期

关键词：

D O I：

10.1038/nrc2190

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Although most lung cancers are a result of smoking, approximately 25% of lung cancer cases worldwide are not attributable to tobacco use, accounting for over 300,000 deaths each year. Striking differences in the epidemiological, clinical and molecular characteristics of lung cancers arising in never smokers versus smokers have been identified, suggesting that they are separate entities. This Review summarizes our current knowledge of this unique and poorly understood disease.

引用

收藏

页码：778 / 790

页数：13

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