The effect of tea consumption on oxidative stress in smokers and nonsmokers

被引：72

作者：

Klaunig, JE

Xu, Y

Han, C

Kamendulis, LM

Chen, JS

Heiser, C

Gordon, MS

Mohler, ER

机构：

[1] Indiana Univ, Sch Med, Div Toxicol, Indianapolis, IN 46202 USA

[2] Chinese Acad Prevent Med, Beijing, Peoples R China

来源：

PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE | 1999年 / 220卷 / 04期

关键词：

D O I：

10.1046/j.1525-1373.1999.d01-43.x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

While the anticarcinogenic effects of tea in animal models have been reported by several groups, human epidemiological studies examining tea consumption end cancer prevention have produced equivocal results, The beneficial properties of tea to human health may be related to the antioxidant properties of tea components, However, little evidence has been provided that tea consumption can either increase the antioxidant capacity or decrease oxidative stress in humans. In the present study, the effects of tea treatment (green tea) on biomarkers of oxidative stress were investigated in smokers acid nonsmokers in two volunteer study groups (one in China and the other in United States). Green tea consumption in both study groups decreased oxidative DNA damage (8-OHdG in white blood cells and urine), lipid peroxidation (MDA in urine), and free radical generation (2,3-DHBA in urine) in smokers. Nonsmokers (US study group) also exhibited a decrease in overall oxidative stress.

引用

页码：249 / 254

页数：6