To cross or not to cross: Alternatively spliced forms of the Robo3 receptor regulate discrete steps in axonal midline crossing

被引：13

作者：

Black, Douglas L. ^{[1
]}

Zipursky, S. Lawrence ^{[2
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, MacDonald Res Labs, Howard Hughes Med Inst,Dept Microbiol Immunol & M, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, MacDonald Res Labs, Howard Hughes Med Inst,Dept Biol Chem, Los Angeles, CA 90095 USA

来源：

NEURON | 2008年 / 58卷 / 03期

关键词：

D O I：

10.1016/j.neuron.2008.04.019

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

How growth cones grow toward and then away from intermediate targets is a key issue in axon guidance. In this issue of Neuron, Tessier-Lavigne and colleagues demonstrate that two different spliced isoforms of the Robo3 receptor act sequentially in commissural neuron growth cones to mediate this process at the ventral midline in the vertebrate spinal cord.

引用

页码：297 / 298

页数：2

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